TABLE 4.
Detailed variation patterns observed in each groupa
| Group name |
Variations in P | Variations in M2-1 | Variations in M2-2 | Variations in L | Number of sequences |
|---|---|---|---|---|---|
| R1 | G1725E | 12 | |||
| N46S | G1725E | 7 | |||
| N46S | H598Y, G1725E, D1731G | 4 | |||
| P34L | N46S | N215S, G1725E | 3 | ||
| N46S | 3 | ||||
| H597Y, G1725E | 3 | ||||
| N46S | H598Y, D1731G | 2 | |||
| V335I, G1725E | 2 | ||||
| H598Y | 2 | ||||
| I66T | V335I, G1725E | 2 | |||
| I66T | V335I | 1 | |||
| N46S | H598Y, G1725E | 1 | |||
| V335I | 1 | ||||
| R2 | T69I | C26Y | S1723G, A1927T, V1943D | 9 | |
| T69I | C26Y | I139T, S1723G, A1927T, V1943D | 3 | ||
| T69I | C26Y | T179A, S1723G, A1927T, V1943D | 1 | ||
| T69I | C26Y | S1723G, V1943D | 1 | ||
| S1723G, V1943D | 1 | ||||
| T179A, S1723G, V1943D | 1 | ||||
| T179A | 1 | ||||
| R3 | N143D, T179S, I1653V, K1661N | 12 | |||
| L37P | N143D, T179S, I1653V, K1661N | 4 | |||
| N143D, T179S, S1593N, I1653V, K1661N, S1789F, Y2163N | 4 | ||||
| N174S, T180A, S182G | N143D, T179S, I1653V, K1661N | 3 | |||
| S100L, N143D, T179S, L935M, I1653V, K1661N | 3 | ||||
| N143D, T179S, I1653V, K1661N, A2014T, Y2163N | 2 | ||||
| S100L, N143D, T179S, L935M, I1653V, K1661N, H1707Q | 2 | ||||
| N143D, T179S, I1653V, K1661N, A2014T | 1 | ||||
| S100L, T179S, L935M, I1653V, K1661N, H1707Q | 1 | ||||
| R4 | T92M | T79A | L835M | 6 | |
| T92M | T79A | A173S, L835M | 3 | ||
| T92M | N547S, L835M, P1720L, V1941I | 3 | |||
| R5 | N59S | R511K, R1759K | 3 | ||
| R6 | 2 |
a
N is not included here as no significant recurrence of non-synonymous variations were observed.