TABLE 5.

Clinical signs and fecal virus shedding of piglets after challenge with 1 mL of the virulent PDCoV CH/XJYN/2016-P6 (1 × 10^4.5 TCID₅₀/mL)^a

dpi	Immunization groupb (n = 5)			Challenged control groupc (n = 4)
	CTd	Average FCf	NPe	CT	Average FC	NP
0	31.90 ± 0.75	0	0/5	33.58 ± 1.36	0	0/4
1	34.50 ± 0.76			33.5 ± 0.22	0	0/4
2	34.10 ± 1.10			29.97 ± 2.26	0.75 ± 0.96	2/4
3	33.50 ± 1.59			28.61 ± 0.88	1.00 ± 1.15	2/4
4	35.49 ± 1.69			26.74 ± 0.91	1.25 ± 0.50	4/4
5	34.09 ± 0.48			29.70 ± 1.20	1.25 ± 0.50	2/4
6	32.92 ± 1.66			33.56 ± 0.32	0.50 ± 0.58	0/4
7	32.86 ± 1.31			33.07 ± 1.33	0.50 ± 0.58	0/4

^a CT value: the mean cycle threshold value; dpi: days post-inoculation; FC: fecal consistency; NP: number of PDCoV-positive pigs.

^b Piglets were intramuscularly injected with 1 mL of the PDCoV P240 (10^8.5 TCID₅₀/mL).

^c Piglets were intramuscularly injected with 1 mL of PBS.

^d A critical point was set at 30; CT values greater than 30 were considered negative.

^e Number of PDCoV-positive piglets.

^f Score: 0 = normal; 1 = pasty; 2 = semiliquid; 3 = liquid. A score greater than or equal to one was considered diarrhea.