Table 2.
Overview of studies on non-tuberculous mycobacteria in China.
|
Province |
Study period | NTM isolation rate (%) | Predominant species | Age ratio of NTM-PD patients | Complications of NTM- PD patients | Clinical symptoms of NTM-PD patients | Ref. |
|---|---|---|---|---|---|---|---|
| Beijing (north region) | 2019 | 6.5 |
M. intracellulare (24.69 %) M. abscessus (24.69 %) M. kansasii (19.75 %) |
0–40:32.10 % 40–60:13.58 % ≥60:54.32 % |
NA | NA | [40] |
| Tianjin (north region) | 2018～2019 | NA |
M. intracellulare (29.08 %) M. chelonae/abscessus (26.60 %) M. kansasii (23.41 %) |
15–40:26.60 % 40–60:29.79 % ≥60:43.62 % |
NA | NA | [41] |
| Jilin (north region) | 2017～2018 | 2.68 |
M. intracellulare (40.59 %) M. kansasii (26.73 %) M. avium (4.95 %) |
≤40:5.94 % 40–60:21.78 % ≥60:72.28 % |
NA | NA | [42] |
| Liaoning (north region) | 2016～2021 | 3.95 |
M. intracellulare (55.91 %) M. abscessus (25.20 %) M. kansasii (8.66 %) |
NA | TB:4.85 % COPD:4.85 % Diabetes:10.68 % Cancer:5.83 % |
NA | [43] |
| Shandong (north region) | 2015～2019 | 11.6 |
M. intracellulare (69.77 %) M. kansasii (12.71 %) M. abscessus (9.89 %) |
＜45:15.25 % 45–60:35.88 % 60–90:48.87 % |
NA | NA | [44] |
| Henan (north region) | 2018～2020 | 3.93 |
M. intracellulare (74.93 %) M. kansasii (9.37 %) M. abscessus (5.79 %) |
<50:22.87 % ≥50:77.13 % |
NA | NA | [45] |
| Shaanxi (north region) | 2019～2021 | 3.5 |
M. intracellulare (36.7 %) M. chelonae/abscessus (26.6 %) M. kansasii (25.0 %) |
14–39:32.58 % 40–65:44.94 % >65:19.10 % |
NA | Cough/Expectoration:82.56 % Hemoptysis:27.91 % Fever:36.05 % Asthma:48.84 % |
[46] |
| Gansu (north region) | 2012～2014 | 4.91 |
M. intracellulare (72.09 %) M. kansasii (6.97 %) |
NA | NA | NA | [47] |
| Xinjiang (north region) | 2009～2011 | 4.98 |
M. avium/intracellulare (43.72 %) M. chelonae/abscessus (13.12 %) |
NA | NA | NA | [48] |
| Chongqing (south region) | 2016～2017 | NA |
M. abscessus (38.75 %) M. intracellulare (31.25 %) M. fortuitum (17.50 %) |
＜30:23.18 % 30–40:10.53 % 40–50:22.11 % 50–60:15.79 % 60–80:25.28 % |
NA | NA | [49] |
| Sichuan (south region) | 2016～2021 | 2.75 |
M. chelonae/abscessus (31.06 %) M. avium (26.52 %) M. intracellulare (26.52 %) |
＜20:3.4 % 20–40:27.3 % 40–60:40.2 % ≥60:29.3 % |
AIDS:14.8 % Bronchiectasis:18.2 % COPD:3.8 % Diabetes:6.1 % |
NA | [50] |
| Hubei (south region) | 2016～2020 | 6.66 |
M. intracellulare (37.88 %) M. abscessus (13.63 %) M. gordonae (5.01 %) |
<35:10.22 % 35–54:23.65 % 55–64:24.05 % >64:42.09 % |
Bronchiectasis:11.22 % COPD:4.21 % Cancer:1.20 % AIDS:0.40 % |
NA | [51] |
| Anhui (south region) | 2021～2022 | 8.2 |
M. intracellulare (74.5 %) M. abscessus (13.6 %) M. kansasii (7.6 %) |
20–39:5.5 % 40–59:36.7 % ≥60:57.8 % |
Bronchiectasis:33.76 % COPD:13.92 % AIDS: 13.92 % Cancer:2.53 % Diabetes:5.06 % |
Cough/Expectoration:71.73 % Hemoptysis:21.94 % Fever:10.97 % Asthma:16.88 % |
[52] |
| Jiangsu (south region) | 2017～2020 | 22.3 |
M. intracellulare (60.7 %) M. chelonae/abscessus (16.1 %) M. avium (10.7 %) |
NA | NA | NA | [53] |
| Shanghai (south region) | 2017～2018 | NA |
M. intracellulare (54.4 %) M. abscessus (22.2 %) M. kansasii (7.8 %) |
NA | NA | Cough:83.58 % Expectoration:80.60 % Hemoptysis:25.37 % Fever:47.76 % Dyspnea:22.39 % |
[54] |
| Zhejiang (south region) | 2009～2014 | 25.8 |
M. intracellulare (60.74 %) M. kansasii (13.33 %) M. avium (4.44 %) |
15–35:16.1 % 35–45:13.6 % 45–55:23.5 % 55–65:19.8 % ≥65:31.5 % |
NA | NA | [55] |
| Fujian (south region) | 2016～2019 | 6.35 |
M. intracellulare (65.73 %) M. chelonae/abscessus (18.78 %) M. kansasii (4.23 %) |
NA | NA | NA | [56] |
| Jiangxi (south region) | 2017～2020 | NA |
M. avium (50 %) M. intracellulare (21.15 %), M. chelonae/abscessus (14.23 %) |
NA | Bronchiectasis:21.15 % COPD:19.23 % AIDS: 3.85 % Cancer:28.85 % Diabetes:6.73 % |
Cough:53.85 % Expectoration:40.38 % Hemoptysis:18.27 % Fever:32.69 % |
[57] |
| Hunan (south region) | 2019～2020 | 8.06 |
M. abscessus (38.29 %), M. intracellulare (33.14 %) M. avium (12.19 %) |
NA | NA | NA | [58] |
| Guizhou (south region) | 2012～2013 | 2.64 |
M. intracellulare (32.26 %), M. chelonae/abscessus (29.03 %) M. avium (25.81 %) |
NA | NA | NA | [59] |
| Yunnan (south region) | 2013～2015 | 1.61 |
M. intracellulare (44.83 %) M. abscessus (27.59 %) M. avium (11.49 %) |
＜20:1.15 % 20–39:18.39 % ≥40:80.46 % |
NA | NA | [60] |
| Guangdong (south region) | 2018～2019 | 30.3 |
M. chelonae/abscessus (41.2 %) M. avium/intracellulare (40.5 %) |
＜30: 19.35 % 30–40:10.99 % 40–50:14.09 % 50–60:21.98 % 60–70:24.43 % ＞70:12.09 % |
NA | NA | [61] |
| Hainan (south region) | 2016～2021 | 13.4 |
M. intracellulare (39.49 %) M. chelonae/abscessus (32.91 %) M. avium (7.59 %) |
≤40:8.9 % ＞40:91.1 % |
NA | NA | [62] |
| Taiwan (south region) | 2000～2012 | 56.9 |
M. avium/intracellulare (41.51 %) M. abscessus (30.81 %) M. fortuitum (13.36 %) |
NA | NA | NA | [63] |