TABLE E1.

Karnofsky performance scale index

Index description	General category
10%-Moribund, fatal processes progressing rapidly	Severe limitation: unable to care for self; requires equivalent of institutional or hospital care; disease may be progressing rapidly (severe limitation)
20%-Very sick, hospitalization necessary: active treatment necessary
30%-Severely disabled: hospitalization is indicated, death not imminent
40%-Disabled: requires special care and assistance
50%-Requires considerable assistance and frequent medical care	Moderate limitation: unable to work; able to live at home and care for most personal needs; varying amount of assistance needed (moderate limitation)
60%-Requires occasional assistance but is able to care for needs
70%-Cares for self: unable to carry on normal activity or active work
80%-Normal activity with effort: some symptoms of disease	Mild limitation: able to carry on normal activity and to work; no special care needed (mild limitation)
90%-Able to carry on normal activity: minor symptoms of disease
100%-Normal, no complaints, no evidence of disease