TABLE 2.
Comparisons by secondary peristaltic contractile responses among symptomatic post-fundoplication patients.
| Normal and Borderline CRs | Impaired/disordered and absent CRs | |
|---|---|---|
| n (%) | 44 (51) | 41 (47) |
| FLIP metrics | ||
| Maximum EGJ diameter, mm | 17.4 (15.6–19.6) | 15.4 (12.0–18.1)* |
| EGJ distensibility index (EGJ-DI), mm2/mmHg | 4.3 (2.7–5.4) | 2.6 (1.7–3.7)* |
| Pressure, 60mL fill volume, mmHg | 44.1 (35.0–53.3) | 35.3 (26.1–43.8)* |
| FLIP EGJ opening classification, n (%) | ||
| Normal EGJ opening | 29 (66) | 18 (44) |
| Borderline EGJ opening | 13 (30) | 16 (39) |
| Reduced EGJ opening | 2 (5) | 7 (17) |
| Esophagram completed, n (%) | 23 (52) | 27 (66) |
| Used barium tablet, n (%) | 16 (70) | 16 (59) |
| Tablet impaction, n (%) | 2 (13) | 5 (31) |
| TBE completed, n (%) | 13 (57) | 15 (56) |
| TBE: 1-min column height, cm | 0.0 (0.0–0.0) | 0.0 (0.0–14.1)* |
| TBE: 5-min column height, cm | 0.0 (0.0–0.0) | 0.0 (0.0–7.45)* |
| HRM completed, n (%) | 33 (75) | 29 (71) |
| HRM metrics | ||
| Supine IRP, mmHg | 12.3 (8.5–17.4) | 17.0 (14.1–21.0)* |
| Upright IRP, mmHg | 13.0 (8.5–20.7) | 15.0 (12.3–19.0) |
| Basal EGJ Pressure, mmHg | 16.0 (10.0–23.0) | 13.0 (9.0–22.0) |
| HRM peristalsis/contractility–CCv4.0, n (%) | ||
| Normal peristalsis | 24 (73) | 13 (45)* |
| Ineffective esophageal motility | 5 (15) | 9 (31) |
| Absent contractility | 1 (3) | 6 (21)* |
| Hypercontractile | 2 (6) | 0 (0) |
| Premature | 1 (3) | 1 (3) |
| symptom scores | ||
| GerdQ score, [n (%) completed GerdQ] | 9 (7–12) [25 (57)] | 9 (7–10) [22 (54)] |
| BEDQ score, [n (%) completed BEDQ] | 17 (13–24) [27 (61)] | 11 (7–17) [23 (56)] |
| EHAS score, [n (%) completed EHAS] | 37 (30–41) [21 (48)] | 31 (22–39) [23 (56)] |
Note:
*
p <0.05 in comparison with normal/borderline CRs.
Abbreviations: CCv4.0, Chicago classification version 4.0; EGJ, esophagogastric junction; EHAS, esophageal hypervigilance and anxiety scale; FLIP, functional lumen imaging probe; GerdQ, GERD questionnaire; HRM, high-resolution manometry; IRP, integrated relaxation pressure; TBE, timed barium esophagram.