Skip to main content
. 2024 Aug 20;19(8):e0308838. doi: 10.1371/journal.pone.0308838

Fig 4. Physiological pathways and connections between cytokines and growth factors that demonstrated sex differences.

Fig 4

Connections between nine cytokines and growth factors that demonstrated some sex differences, displayed using STRING v11.5 analysis. Nodes are coloured to represent different functional pathways and to identify the biomarker as either a growth factor (green), or cytokine (blue). CASP1 (IL-1β), IL-3, TNF (TNF-α), VEGFA (VEGF), CCL2 (MCP-1), EGF, ANG (Angiogenin), CXCL12 (SDF-1), and NKSF1 (IL-12) are connected using green (text mining), pink (experimentally determined), blue (from curated databases), and grey (co-expression) lines.