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. 2024 Jul 29;81(1):318. doi: 10.1007/s00018-024-05350-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Locomotor recovery in nude rats following cell transplantation. (a). Transplanted sites of ESC-DI-PNPs in nude rats. (b). Evoked action potentials were observed following engraftment of PNPs. (c). BBB score of SCI nude rats with or without transplantation of ESC-DI-PNPs. (d). Results of ladder climbing test. (e, f). Results of BBB and ladder climbing tests following CNO administration in transplantation and vehicle groups. (n = 5; *P < 0.05; **P < 0.01; ***P < 0.001; compared with vehicle groups)