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. 2024 Aug 19;8(5):e325. doi: 10.1097/EE9.0000000000000325

Table 4.

Adjusted association for pesticide exposures (kg) within a 400-m radius of a child’s residence and wheezing symptoms at baseline in the AIRE cohort

Exposure n Wheezing prevalence
(95% CI)
Crude
n Wheezing prevalence
(95% CI)
Min adjusteda
n Wheezing prevalence
(95% CI)
Fully adjustedb
All
 None 194 Ref 194 Ref. 179 Ref.
 Low (<67 kg) 235 0.07(−0.01, 0.14) 235 0.07 (−0.007, 0.14) 222 0.07 (−0.008, 0.15)
 High (≥67 kg) 229 0.09 (0.02, 0.17) 229 0.10 (0.02, 0.17) 213 0.10 (0.03, 0.18)
Sulfur
 None 397 Ref 397 Ref. 371 Ref.
 Low (<80 kg) 133 0.04 (−0.04, 0.12) 133 0.03 (−0.05, 0.11) 123 0.04 (−0.04, 0.12)
 High (≥80 kg) 128 0.12 (0.04, 0.20) 128 0.12 (0.05, 0.20) 120 0.13 (0.05, 0.21)
All minus Sulfur
 None 197 Ref 197 Ref. 182 Ref.
 Low(<34 kg) 232 0.07(−0.005, 0.15) 232 0.07 (−0.004, 0.15) 221 0.07 (−0.006, 0.15)
 High (≥34 kg) 229 0.08 (0.007, 0.16) 229 0.09 (0.01, 0.16) 211 0.09 (0.02, 0.17)
Chlorpyrifos
 None 530 Ref 530 Ref. 492 Ref.
 Low (<2 kg) 62 0.07(−0.03, 0.17) 62 0.06 (−0.04, 0.16) 59 0.07 (−0.04, 0.17)
 High (≥2 kg) 66 0.15 (0.04, 0.25) 66 0.15 (0.05, 0.26) 63 0.16 (0.06, 0.27)
Glyphosate
 None 360 Ref 360 Ref. 332 Ref.
 Low (<7 kg) 148 0.02 (−0.05, 0.10) 148 0.02 (−0.05, 0.10) 138 0.04 (−0.04, 0.12)
 High (≥7 kg) 150 0.09 (0.01, 0.17) 150 0.09 (0.01, 0.16) 144 0.10 (0.02, 0.18)

Low and high categories split at the median (kg) for those with pesticide exposures greater than 0 within a 400-m radius of the residence. None indicates no pesticide applications were applied within a 400-m radius of the child’s residence.

a

Minimally adjusted for sex and language of survey.

b

Fully adjusted for sex, language of survey, health insurance, parent/guardian education, and exposure to environmental smoking.

Ref indicates reference group.