Table 1.
Effects of shifting Canton-S female flies from a high (H)- to a low (L)-calorie diet on longevity compared to longevity of flies on lifelong high-calorie diet
| Food | Time on L diet |
N (n censored) |
Mean LS (% change) |
X2 | p | Maximal LS (% change) |
|---|---|---|---|---|---|---|
| H | Lifelong | 402 (12) | 46.7 (− 91.2) | 751.9572 | < 0.0001* | 68.2 (− 62.2) |
| L | Lifelong | 439 (6) | 89.3 | 110.6 | ||
| H | Lifelong | 402 (12) | 46.7 (− 84.2) | 423.5131 | < 0.0001* | 68.2 (− 53.9) |
| HLD20 | D20 | 207 (4) | 86.0 | 105 | ||
| H | Lifelong | 402 (12) | 46.7 (− 26) | 47.8706 | < 0.0001* | 68.2 (− 59) |
| HLD50 | D50 | 217 (7) | 59.1 | 108.2 | ||
| H | Lifelong | 402 (12) | 46.7 (− 13.9) | 16.5431 | 0.0742 | 68.2 (− 53.8) |
| HLD60 | D60 | 211 (10) | 53.2 | 104.9 |
L low-calorie diet, H high-calorie diet, HLD20 flies shifted from a high- to a low-calorie diet at day 20, HLD50 flies shifted from a high- to a low-calorie diet at day 50, HLD60 flies shifted from a high to low-calorie diet at day 60
N = Number of flies in experiment used for calculating mean and maximal lifespan
n censored = number of flies that died between 0 and 10 days, and are not included in listed N and are not included in calculation of mean and maximal lifespan. The total number of flies in experiments on day 0 is N plus n flies)
*Statistically significant