Table 2.
Effects of shifting Canton-S female flies from a low (L)- to a high (H)-calorie diet on longevity compared to longevity of flies on lifelong low-calorie diet
| Food | Time on L diet |
N (n censored) |
Mean LS (% change) |
X2 | p | Maximal LS (% change) |
|---|---|---|---|---|---|---|
| L | Lifelong | 439 (6) | 89.3 (− 48) | 751.9572 | < 0.0001* | 110.6 (− 38) |
| H | Lifelong | 402 (12) | 46.7 | 68.2 | ||
| L | Lifelong | 439 (6) | 89.3 (− 44) | 565.7714 | < 0.0001* | 110.6 (− 31) |
| LHD20 | D20 | 207 (6) | 49.8 | 76.3 | ||
| L | Lifelong | 439 (6) | 89.3 (− 35) | 526.5062 | < 0.0001* | 110.6 (− 30) |
| LHD50 | D50 | 226 (4) | 58.0 | 77.9 | ||
| L | Lifelong | 439 (6) | 89.3 (− 31) | 454.1635 | < 0.0001* | 110.6 (− 26) |
| LHD60 | D60 | 218 (6) | 62.0 | 82.2 |
L low-calorie diet, H high-calorie diet, LHD20 flies shifted from a low- to high-calorie diet at day 20, LHD50 flies shifted from a low- to a high-calorie diet at day 50, LHD60 flies shifted from a low- to a high-calorie diet at day 60, N number of flies in experiments used for calculating mean and maximal lifespan, n censored number of flies that died between 0 and 10 days, and are not included in listed N and are not included in calculation of mean and maximal lifespan. The total number of flies in experiments on day 0 is N plus n flies)
*Statistically significant