Fig. 3.

Effect of age and CMV serostatus on numbers of T cell subsets in blood. The interaction of age and CMV serostatus for each T cell subset is analyzed by ANOVA (inset table). A Comparison of total CD4 and CD8 T cells between the age/CMV groups. B Comparison of T cell subsets between the age/CMV groups. Tn, naïve T cells; Tcm, central memory T cells; Tem, effector memory T cells; Temra, RA-positive effector memory T cells. Black circle and line, age 21–40; red square and line, age 65 + . Neg, anti-CMV antibody negative; low, anti-CMV antibody titer low; high, anti-CMV antibody titer high. Vertical double-head arrows (blue) represent the comparison between age groups regardless of CMV status and horizontal double-head arrows (Green) represent the comparison between CMV groups regardless of age. Data are presented as mean ± SE. p-values for group comparisons were adjusted by Holm’s method. Statistical significance between age groups is shown as #p < 0.05, ##p < 0.01, and ###p < 0.001. Statistical significance between CMV groups is shown as *p < 0.05, **p < 0.01, and ***p < 0.001