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. Author manuscript; available in PMC: 2025 Jul 1.
Published in final edited form as: Mol Psychiatry. 2024 Feb 21;29(7):2095–2104. doi: 10.1038/s41380-024-02470-3

Table 3.

Mixed Effects Models for the (a) Left Arcuate-FT and (b) Right Arcuate-FP Estimating Receptive Language

(a) Left Arcuate-FT (b) Right Arcuate-FP
Estimate (SE) t-statistic df p-value 95% CI Estimate (SE) t-statistic df p-value 95% CI
Intercept −0.649 (3.67) −0.177 32.2 0.861 (−8.12, 6.82) −0.73 (3.23) −0.226 27.5 0.823 (−7.36, 5.9)
HL: Negative 5.9 (3.52) 1.675 43.7 0.101 (−1.2, 13) 5.692 (3.18) 1.793 30.8 0.083 (−0.79, 12.18)
LL: Negative 7.975 (3.79) 2.106 38.2 0.042 (0.31, 15.64) 7.033 (3.45) 2.038 29.2 0.051 (−0.02, 14.09)
6- to 12-months 3.853 (2.88) 1.339 95 0.184 (−1.86, 9.57) 4.454 (2.93) 1.52 25.8 0.141 (−1.58, 10.49)
12- to 24-months −5.144 (5.91) −0.87 22.5 0.393 (−17.41, 7.12) −3.378 (7.28) −0.464 8.7 0.654 (−20.17, 13.42)
Fractional Anisotropy 1.811 (1.03) 1.753 32.4 0.089 (−0.29, 3.91) 1.925 (0.95) 2.018 26.7 0.054 (−0.04, 3.88)
HL: Neg. x 6–12 1.645 (0.72) 2.272 172.7 0.024 (0.22, 3.07) 1.65 (0.7) 2.346 154.2 0.02 (0.26, 3.04)
LL: Neg x 6–12 2.701 (0.8) 3.386 108.2 0.001 (1.12, 4.28) 2.608 (0.78) 3.341 89.1 0.001 (1.06, 4.16)
HL: Neg. x 12–24 5.746 (0.8) 7.178 926.1 < 0.001 (4.17, 7.32) 5.767 (0.82) 7.017 433.5 < 0.001 (4.15, 7.38)
LL: Neg. x 12–24 6.078 (0.87) 6.96 739.2 < 0.001 (4.36, 7.79) 6.08 (0.89) 6.825 438.1 < 0.001 (4.33, 7.83)
HL: Neg. x FA −1.578 (0.99) −1.591 44.1 0.119 (−3.58, 0.42) −1.59 (0.94) −1.699 30.9 0.099 (−3.5, 0.32)
LL: Neg. x FA −2.102 (1.07) −1.964 37.6 0.057 (−4.27, 0.07) −1.92 (1.02) −1.885 28.6 0.07 (−4.01, 0.17)
6–12 x FA −0.109 (0.77) −0.142 65 0.887 (−1.64, 1.42) −0.286 (0.8) −0.359 23.3 0.723 (−1.93, 1.36)
12–24 x FA 1.976 (1.4) 1.415 27 0.168 (−0.89, 4.84) 1.704 (1.75) 0.971 9.6 0.355 (−2.26, 5.67)

Note. Reference groups are High-Likelihood ASD, Female, and Maternal Education Less than a college Degree. The covariates of sex, maternal education, and site of data collection were controlled for in the current model. HL: Negative = High-Likelihood not diagnosed with ASD, LL: Negative = Low Likelihood not diagnosed with ASD, FA = Fractional Anisotropy, WM = White Matter.