Table 2.
Investigation of alterations in the mean retinal thickness across distinct retinal layers throughout the visits with exclusion of patients with occurrence of cystoid macular edema adjusted for patient age, best corrected visual acuity, lens status of the fellow eye (phakic and pseudophakic) and duration of surgery (n = 36).
| Retinal layer | ETDRS | Presented are the least square mean differences and 95 % confidence intervals (Bonferroni corrected) in μm |
|||||
|---|---|---|---|---|---|---|---|
| Pre OP - Day 1 | Pre OP - Month 1 | Pre OP - Month 3 | Day 1 - Month 1 | Day 1 - Month 3 | Month 1 - Month 3 | ||
| RNFL | CS | 0.03 (−0.93, 0.99) | 0.34 (−0.78, 1.45) | 0.57 (−0.6, 1.74) | 0.31 (−1, 1.61) | 0.54 (−0.98, 2.06) | 0.23 (−0.91, 1.37) |
| IR | 0.15 (−0.3, 0.6) | −1.6 (-2.55, -0.64) | −1.29 (-2.01, -0.57) | −1.75 (-2.72, -0.78) | −1.44 (-2.2, -0.69) | 0.3 (−0.23, 0.84) | |
| GCL | CS | 0.66 (−0.71, 2.02) | −0.58 (−1.7, 0.53) | −0.33 (−1.25, 0.6) | −1.24 (−2.66, 0.19) | −0.98 (−2.48, 0.52) | 0.25 (−0.74, 1.25) |
| IR | −0.52 (−1.68, 0.64) | −3.43 (-4.65, -2.2) | −2.96 (-3.97, -1.96) | −2.91 (-4.34, -1.47) | −2.45 (-3.64, -1.25) | 0.46 (−0.2, 1.13) | |
| IPL | CS | −0.48 (−1.91, 0.94) | −1.71 (-2.89, -0.53) | −1.43 (-2.34, -0.52) | −1.23 (−2.78, 0.32) | −0.95 (−2.48, 0.59) | 0.28 (−0.54, 1.1) |
| IR | −0.26 (−1.16, 0.64) | −2.64 (-3.55, -1.73) | −2.23 (-3.18, -1.29) | −2.39 (-3.45, -1.32) | −1.98 (-2.7, -1.25) | 0.41 (−0.48, 1.29) | |
| RNFL + GCL + IPL | CS | 0 (−2.1, 2.11) | −2.02 (−4.52, 0.48) | −1.24 (−3.09, 0.61) | −2.02 (−5.04, 0.99) | −1.25 (−3.72, 1.23) | 0.78 (−1.04, 2.6) |
| IR | −0.59 (−2.12, 0.94) | −7.64 (-9.96, -5.32) | −6.37 (-8.15, -4.6) | −7.05 (-9.91, -4.19) | −5.78 (-8.09, -3.48) | 1.26 (−0.16, 2.69) | |
| INL | CS | 0.07 (−2.36, 2.5) | −1.7 (−3.98, 0.58) | −1.52 (−3.58, 0.54) | −1.77 (−4.56, 1.02) | −1.59 (−4.16, 0.98) | 0.18 (−1.15, 1.51) |
| IR | 0.43 (−0.9, 1.76) | −1.81 (-3.08, -0.54) | −0.77 (−1.84, 0.3) | −2.24 (-3.77, -0.71) | −1.2 (-2.39, -0.01) | 1.04 (0.02, 2.05) | |
| OPL | CS | 0.82 (−1.87, 3.52) | 0.31 (−2.69, 3.32) | 1.91 (−1.49, 5.3) | −0.51 (−3.8, 2.78) | 1.08 (−1.51, 3.67) | 1.59 (−0.43, 3.62) |
| IR | 0.48 (−1.7, 2.66) | 1.42 (−0.59, 3.44) | 1.35 (−0.7, 3.4) | 0.94 (−0.6, 2.48) | 0.87 (−0.34, 2.07) | −0.08 (−1.26, 1.11) | |
| INL + OPL | CS | 0.57 (−3.47, 4.6) | −1.31 (−5.39, 2.77) | 0.64 (−3.57, 4.85) | −1.88 (−6.34, 2.59) | 0.08 (−3.42, 3.57) | 1.95 (−0.38, 4.29) |
| IR | 0.87 (−1.57, 3.3) | −0.36 (−2.67, 1.95) | 0.6 (−1.66, 2.86) | −1.23 (−3.65, 1.2) | −0.27 (−2.08, 1.54) | 0.96 (−0.71, 2.62) | |
| ONL | CS | 2.92 (−1.89, 7.73) | −7.26 (-13.05, -1.48) | −6.12 (-10.67, -1.56) | −10.18 (-16.25, -4.12) | −9.04 (-12.85, -5.23) | 1.14 (−3.93, 6.21) |
| IR | −0.6 (−3.15, 1.94) | −7.43 (-10.37, -4.5) | −6.23 (-8.93, -3.53) | −6.83 (-9.61, -4.05) | −5.63 (-7.74, -3.52) | 1.2 (−0.4, 2.8) | |
| IRL | CS | 4.51 (1.32, 7.71) | −11.13 (-20.36, -1.9) | −7.51 (-11.79, -3.24) | −15.64 (-25.33, -5.96) | −12.02 (-17.24, -6.81) | 3.62 (−3.34, 10.58) |
| IR | 0.28 (−2.71, 3.27) | −15.31 (-20.37, -10.25) | −11.62 (-15.28, -7.96) | −15.59 (-21.65, -9.52) | −11.9 (-16.47, -7.33) | 3.69 (0.38, 7) | |
| TR | CS | 4.45 (0.7, 8.19) | −11.88 (-22.34, -1.43) | −7.22 (-12.3, -2.14) | −16.33 (-27.59, -5.07) | −11.67 (-17.67, -5.67) | 4.66 (−3.34, 12.66) |
| IR | 1.76 (−3.12, 6.65) | −15.91 (-21.64, -10.18) | −11.71 (-16.69, -6.74) | −17.68 (-25.68, -9.68) | −13.48 (-20.36, -6.59) | 4.2 (−0.53, 8.94) | |
Legend: ETDRS = Early Treatment Diabetic Retinopathy Study; CS= Central Subfield; IR= Inner Ring; RNFL = Retinal Nerve Fiber Layer; GCL = Ganglion Cell Layer; IPL = Inner Plexiform Layer; RNFL-GCL-IPL = RNFL + GCL + IPL combined; INL =Inner Nuclear Layer; OPL = Outer Plexiform Layer; INL-OPL =INL + OPL combined; ONL =Outer Nuclear Layer; IRL = Inner Retinal Layer; TR = Total Retina; Bold: Disparity is statistically significant (p < 0.05).