Table 2.
TMS measures.
| Effect of | rTMSSHAM |
rTMSREAL |
rTMSREAL |
rTMSSHAM |
||||
|---|---|---|---|---|---|---|---|---|
| rPMSSHAM |
rPMSREAL |
rPMSSHAM |
rPMSREAL |
|||||
|
Pre |
Post |
Pre |
Post |
Pre |
Post |
Pre |
Post |
|
| Baseline | sham-sham | real-real | real-sham | |||||
| Test MEP | ||||||||
|
mV Mean |
2.48 | 1.83 | 4.84 | 5.15 | 2.87 | 2.31 | 3.91 | 5.32 |
| SD | 1.78 | 0.83 | 2.91 | 3.05 | 2.33 | 1.76 | 2.76 | 3.02 |
| Post in % pre-stimulation (same session) | ||||||||
| Mean | – | 73.8 | – | 106.4 | – | 80.7 | – | 136.1 |
| SD | – | 33.5 | – | 62.9 | – | 61.5 | – | 77.3 |
| Pre in % pre-stimulation of previous session | ||||||||
| Mean | – | – | 195.1 | – | 59.3 | – | 136.2 | – |
| SD | – | – | 117.3 | 48.1 | 96.2 | – | ||
| SICI-conditioned MEP and log-transformed data | ||||||||
|
% test MEP Mean |
26.6 | 80.3 | 60.4 | 56.4 | 78.4 | 61.8 | 6.4 | 74.8 |
| SD | 28.4 | 32.7 | 46.5 | 51.9 | 71 | 58.8 | 3.9 | 57.6 |
|
Log-data Mean |
1.23 | 1.87 | 1.62 | 1.50 | 1.69 | 1.56 | 0.73 | 1.73 |
| SD | 0.41 | 0.17 | 0.42 | 0.57 | 0.49 | 0.50 | 0.26 | 0.38 |
| Post in % pre-stimulation (same session, log-data) | ||||||||
| Mean | – | 152.3 | – | 92.4 | – | 92.5 | – | 237.6 |
| SD | – | 13.9 | – | 35.1 | – | 29.4 | – | 52.5 |
| Pre in % pre-stimulation of previous session | ||||||||
| Mean | – | – | 131.7 | – | 104.3 | – | 43.2 | – |
| SD | – | – | 34.1 | 30 | 15.4 | – | ||
| ICF-conditioned MEP % test MEP | ||||||||
| Mean | 141 | 110.6 | 92.2 | 115.3 | 161.2 | 121 | 78.1 | 126 |
| SD | 122.4 | 45.2 | 53.8 | 48.1 | 86.9 | 73.3 | 66.7 | 49.6 |
| Post in % pre-stimulation (same session) | ||||||||
| Mean | – | 78.5 | – | 125.1 | 75 | 161.1 | ||
| SD | – | 32 | – | 52.2 | 45.5 | 63.5 | ||
| Pre in % pre-stimulation of previous session | ||||||||
| Mean | – | – | 65.4 | – | 174.8 | – | 48.5 | – |
| SD | – | – | 38.2 | 94.3 | 41.2 | – | ||
| SICF conditioned MEP % test MEP | ||||||||
| Mean | 1531 | 472 | 4980 | 8211 | 4480 | 1316 | 2122 | 3337 |
| SD | 1561 | 202.1 | 4623 | 7482 | 4155 | 1042 | 1494 | 1822 |
| Post in % pre-stimulation (same session) | ||||||||
| Mean | – | 30.8 | – | 164.9 | – | 29.4 | – | 157.3 |
| SD | – | 13.2 | – | 150 | – | 23.3 | – | 85.8 |
| Pre in % pre-stimulation of previous session | ||||||||
| Mean | – | – | 325.3 | – | 89.96 | – | 47.37 | – |
| SD | – | – | 302 | 83.4 | 33.3 | – | ||
Test MEP was elicited at 120 % RMT for SICI and ICF (paired-pulse TMS at 80/120 % RMT, ISI at 3 and 15 ms, respectively) and at 100 % RMT for SICF (paired-pulse TMS at 100/90 % RMT, ISI at 1 ms). SICI data were log-transformed (non-respect of Gaussian distribution) and % pre-stimulation was calculated on log-data. N: number of measures per timepoint; ISI: inter-stimulus interval; MEP: Motor evoked potential; pre: before stimulation at each session; post: after stimulation at each session; RMT: resting motor threshold; SD: Standard deviation; ICF: intracortical facilitation; SICF: short-interval intracortical facilitation; SICI: short-interval intracortical inhibition. Significant differences for pre/post-stimulation changes (% pre-stimulation) are denoted in Fig. 3.