Fig. 6.

Functional effects of MZT2A overexpression in Kidney Cancer Cell cells. (A, B) Relative mRNA and protein expression of overMZT2A-transfected kidney cancer cells. (C) Cell proliferation monitoring images. (D) BrdU incorporation assay showed increase of cell proliferation in MZT2A-upregulated KIRC cells. Flow cytometry analysis of Cell cycle (E) and cell apoptosis (F). (G) Western blot analysis of CDK6, CDK4, cyclinD1, Bax, and Bcl-XL expression in MZT2A-overexpressing cells. The original images were shown in Fig. S6. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001.