1. Overview of the 10 studies investigating alpha blockers as monotherapy.
Alpha blocker | Dose range (mg/day) | Number of studies | Alpha patients (n) | Placebo patients (n) | Mean duration (weeks) | Mean age (years) | Baseline BP (mm Hg) |
Bunazosin | 3‐12 | 1 | 12 | 4 | 8.0 | Not reported | 163.3/102.8 |
Doxazosin | 2‐12 | 3 | 347 | 125 | 7.1 | 58.1 | 157.8/101.4 |
Prazosin | 2.5‐20 | 2 | 108 | 32 | 4.2 | 55.1 | 151.9/99.9 |
Terazosin | 5‐20 | 4 | 203 | 159 | 4.0 | Not reported | 155.4/101.4 |