2. Summary of the blood pressure lowering efficacy of alpha blockers.
Alpha blocker | Lowest effective dose (mg/day) | Lowest dose with near maximal BP lowering (mg/day) | Near maximal trough SBP lowering | Near maximal trough DBP lowering | Trough SBP lowering (mm Hg), 95% CI | Trough DBP lowering (mm Hg), 95% CI |
Bunazosin | Not estimable | Not estimable | Not estimable | Not estimable | Not estimable | Not estimable |
Doxazosin | 4 | Not estimable | Not estimable | Not estimable | ‐6.42 (‐10.12, ‐2.80) | ‐3.53 (‐4.99, ‐2.07) |
Prazosin | 10 | Not estimable | Not estimable | Not estimable | ‐10.38 (‐16.21, ‐4.56) | ‐6.90 (‐9.79, ‐4.01) |
Terazosin | 5 | Not estimable | Not estimable | Not estimable | ‐6.59 (‐10.22, ‐2.96) | ‐4.40 (‐5.95, ‐2.84) |