Study	Reason for exclusion
Achari 2000	Published paper states BP measurements were taken using standard sphygmomanometer but clinic BP data not reported, only 24‐hour ambulatory BP data. Authors were contacted for clinic BP data. Lead author replied that data for their paper were taken from a terazosin study conducted around 1990 in which a subset of patients had 24‐hour blood pressure monitoring and that he will not be able to provide any additional data as he no longer has access to original terazosin study.
Ames 1989	Alpha blocker dose titrated to BP response every 2 weeks during double‐blind treatment period. Participants were not receiving same dose of alpha blocker.
Ames 1989a	Alpha blocker dose titrated to BP response every 2 weeks during double‐blind treatment period.
Aronow 1977	Fixed titration study but any given dose of alpha blocker was only administered for 2 weeks or less.
Aronow 1978	Fixed titration study but any given dose of alpha blocker was only administered for 2 weeks or less.
Baez 1986	Alpha blocker dose titrated to BP response during double‐blind treatment period.
Chrysant 1981	Alpha blocker dose was being up‐titrated once weekly or every 2 weeks (not clear) during double‐blind treatment period. Participants were not receiving same dose of alpha blocker.
Cohen 1987	Alpha blocker dose titrated to BP response at weekly intervals during double‐blind treatment period. Participants were not receiving same dose of alpha blocker.
Courtney 2003	Alpha blocker dose titrated to BP target during double‐blind treatment period. Participants were not receiving same dose of alpha blocker.
Gould 1981	Alpha blocker dose titrated to BP response during double‐blind treatment period. Participants were not receiving same dose of alpha blocker.
Materson 1993	Alpha blocker dose titrated to BP response every 2 weeks during double‐blind treatment period. Participants were not receiving same dose of alpha blocker.
Mroczek 1974	Alpha blocker dose titrated to BP response during double‐blind treatment period. Participants were not receiving same dose of alpha blocker.
Nash 1987	Alpha blocker dose titrated to BP response during double‐blind treatment period. Participants were not receiving same dose of alpha blocker.
Romero 1992	Alpha blocker dose titrated to BP response at week 1 of double‐blind treatment period. Participants were not receiving same dose of alpha blocker.
Shionoiri 1997	Alpha blocker dose titrated to BP response during double‐blind treatment period. Participants were not receiving same dose of alpha blocker.
Smyth 1988	Alpha blocker dose titrated to BP response during double‐blind treatment period. Participants were not receiving same dose of alpha blocker.
Svetkey 1988	Alpha blocker dose titrated to BP response at week 4 of double‐blind treatment period. Participants were not receiving same dose of alpha blocker.
Torvik 1986	Alpha blocker dose titrated to BP response during double‐blind treatment period. Participants were not receiving same dose of alpha blocker.
Venter 1991	Alpha blocker dose titrated to BP response during double‐blind treatment period. Participants were not receiving same dose of alpha blocker.
Yasunari 2006	BP measured was measured at least once per month but only BP data at 6 months (week 24) reported. Email sent to lead author (yasunari@med.osaka‐cu.ac.jp) on June 22, 2009 requesting 3 to 12‐week post‐randomization BP data but no reply.