Table 1.
Group | n | Before modeling | After modeling | Post intervention |
---|---|---|---|---|
Control | 12 | 245±7 | 266±11 | 316±15 |
POI | 12 | 244±10 | 253±11a | 286±13b |
SA+POI | 12 | 244±7 | 255±12a | 288±13 |
ZS+POI | 12 | 244±9 | 255±14a | 301±17c |
Notes: control: normal feeding, without any treatment; POI: POI model was induced by intraperitoneal injection of CTX (2 mg/mL) for 15 d; SA + POI: sham acupuncture intervention in CTX-induced POI rats for 4 weeks; ZS+POI: Zhibian (BL54) through Shuidao (ST28) acupuncture intervention in CTX-induced POI rats for 4 weeks. The one-way analysis of variance and least significance difference-t test were used. Compared with the control group, aP < 0.05, bP < 0.01; compared with the POI group, cP < 0.05. POI: premature ovarian insufficiency; CTX: cyclophosphamide; SA: sham acupuncture; ZS: Zhibian (BL54) through Shuidao (ST28) acupuncture.