Table 2.
Changes in serum hormone levels ($\bar{x}±s$)
| Group | n | After modeling | Post-intervention | |||||
|---|---|---|---|---|---|---|---|---|
| FSH (IU/L) |
LH (mIU/mL) |
E2 (pmol/L) |
FSH (IU/L) |
LH (mIU/mL) |
E2 (pmol/L) |
|||
| Control | 12 | 3.1±0.9 | 22.7±6.7 | 39.3±9.8 | 4.0±1.1 | 20.9±5.0 | 43.7±6.1 | |
| POI | 12 | 6.0±1.3a | 36.7±5.4a | 26.0±8.7a | 7.4±1.4a | 36.3±4.2a | 28.0±6.0a | |
| SA+POI | 12 | 5.8±0.9a | 38.8±5.1a | 29.6±6.5a | 7.3±0.9 | 35.2±4.4 | 30.6±6.1 | |
| ZS+POI | 12 | 6.3±0.9a | 36.8±6.2a | 27.1±8.6a | 6.1±0.9b | 30.3±4.4b | 38.0±7.0b | |
Notes: control: normal feeding, without any treatment; POI: POI model was induced by intraperitoneal injection of CTX (2 mg/mL) for 15 d; SA + POI: sham acupuncture intervention in CTX-induced POI rats for 4 weeks; ZS + POI: Zhibian (BL54) through Shuidao (ST28) acupuncture intervention in CTX-induced POI rats for 4 weeks. FSH: follicle-stimulating hormone; LH: luteinizing hormone; E2: estradiol. The one-way analysis of variance and least significance difference-t test were used. Compared with the control group, aP < 0.01; compared with the POI group, bP < 0.01. POI: premature ovarian insufficiency; CTX: cyclophosphamide; SA: sham acupuncture; ZS: Zhibian (BL54) through Shuidao (ST28) acupuncture.