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. 2004 Oct 26;383(Pt 3):551–559. doi: 10.1042/BJ20040054

Figure 7. Structures of (1) doxorubicin and (2) chloroquine diphosphate, two inhibitors of S. aureus DNA ligase.

Figure 7

The IC50 values for inhibition of S. aureus DNA ligase have been determined against these inhibitors using the HPA. For (1), IC50=3.30±0.86 μM; for (2), IC50=1.40±0.07 μM.