Fig. 1.

Presence of EP granules in mouse brain. A Nissl stained coronal section of a mouse brain at bregma -2,45 mm showing EP granules localization. Granules (red dots) are indicated only in the right hemisphere whereas the left hemisphere is used to indicate the name of the different structures. As can be observed, granules were placed along the longitudinal fissure (green line), the quadrigeminal cistern (QCi), and the fissura magna (red line) and concentrated in specific regions numbered from zone 1 to zone 8. B-I Representative images of EP granules in each described region in a representative 3-month-old SAMP8 mouse. (ACi) ambient cistern, (IPCi) interpeduncular cistern. Figure 1A is adapted from [26]. Scale bars: 50 µm