Table 1.
Demographic characteristics of the cohort (N = 212)
| HP cohort (N = 212) | |
|---|---|
| Mean age at ILD diagnosis (SD) | 62.4 (11.4) |
| Male, No. (%) | 102 (48.1) |
| Ethnicity, No. (%) | |
|
Non-Hispanic White Black Hispanic or Latino Asian Unknown |
177 (83.5) 9 (4.2) 11 (5.2) 8 (3.8) 7 (3.3) |
| Ever Smoker, N (%) | 100 (47.2) |
|
Antigen identified Mold antigen Avian antigen Other antigen |
186 (87.8) 104 (49.1) 64 (30.2) 18 (8.5) |
| Professional mold inspection | 20 (9.4) |
| Antigen removal status | |
|
Antigen identified and removed Antigen identified and not removed Antigen not identified |
166 (78.3) 20 (9.4) 26 (12.3) |
| Baseline Lung Function, mean (SD), N | |
| FVC % predicted | 68.6 (18.5), 212 |
| DLCO % predicted | 51.4 (17.7), 212 |
|
HRCT available for scoring Typical HP Compatible HP Indeterminate HP |
212 (100) 136 (64.1) 24 (11.3) 52 (24.5) |
| Fibrotic HP | 190 (89.6) |
| Invasive procedure Performed | 187 (88.2) |
| Surgical Biopsy | 139 (65.6) |
|
TBBx BAL |
92 (43.4) 80 (37.8) |
| GAP score, N (%) | |
|
0–1 2–3 4–5 >5 |
34 (16.0) 92 (43.4) 75 (35.4) 11 (5.2) |
| Confidence HP diagnosis by American Thoracic Society Criteria, N (%) | |
|
Moderate High Definite |
85 (40.1) 33 (15.6) 94 (44.3) |
|
Outcomes Death Transplant Alive at censor date |
81 (38.2) 40 (18.9) 41 (19.3) 131 (61.8) |
| Median transplant-free survival in months | 53.3 |