Table 3. Autoantibodies and complement factors in the 13 cases never positive for ANA in the incident Southeast Norway SLE cohort during 2000–2017 (N=737).
Anti-dsDNA | Case | Anti-ENA | Anti-PL | Low complement | |||||
Anti-SSA | Anti-SSB | Anti-Sm | Anti-CL | LA | Anti-ß2 GPI | C3 | C4 | ||
1 | – | –* | – | – | – | – | – | – | – |
2 | + | + | + | – | + | – | – | + | + |
3 | – | – | – | – | – | + | – | – | – |
4 | + | – | – | + | + | + | + | + | + |
5 | – | + | – | – | – | – | – | – | – |
6 | – | – | – | – | – | – | – | + | – |
7 | – | – | – | – | + | + | + | – | – |
8 | – | + | – | – | – | – | – | – | – |
9 | – | – | – | – | – | + | – | + | – |
10 | – | – | – | – | – | – | – | – | – |
11 | – | – | – | – | – | – | – | – | – |
12 | – | – | – | – | – | – | – | – | – |
13 | – | – | – | – | – | – | – | – | – |
cCase 1 has positive anti-ENA, but negative anti-SSA/SSB.
aCL, anti-cardiolipin; aCL, anti-cardiolipin; ANA, antinuclear antibodies; anti-ß2 GPIanti-beta2glycoprotein Ianti-PL, anti-phospholipid; C3, C3 proteins; C4, C4 proteinsdsDNA, double-stranded DNA; ENA, extractable nuclear antigen; LA, lupus anticoagulantPLphospholipidSSA, Sjögren’s-syndrome-related antigen ASSB, Sjögren’s-syndrome-related antigen B