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. 2004 Aug 24;382(Pt 2):441–449. doi: 10.1042/BJ20040110

Figure 6. Dictyostelium PLB-related sequences in mammals and other organsims.

Figure 6

(A) Sequences related to Dictyostelium PLB in several organisms. Accession numbers for the entries are used to identify the sequences. (B) Cladogram showing the relationship between the different sequences. DD, Dictyostelium discoideum; Mus, mouse; Hu, human; CE, C. elegans; Bos, Bos taurus; Dm, Drosophila; AnaGamb, Anopheles gambiae; Trpan Bru, Trypanosoma brucei. (C) A BLAST (NCBI) search was performed using the D. discoideum PLB sequence. Several sequences were retrieved with 30% identity or less. Alignment using Clustal (EBI) of mouse (Q8BHG8), human (Q8NHP8) and Dictyostelium (Q8MWQ0) sequences illustrates regions of identity (shaded black) and of similarity (shaded grey). The consensus lipase sequence GxSxG, and the region of strong PLB conservation NSGTYN(N/S)Q is indicated (broken line).