Table 3.

Change in frequency of nocturia at weeks 6, 12, 18, and 24.

Study time point	RCT Fem™ UI Mean ± SD (n) Within-group p*	PollenBerry® Mean ± SD (n) Within-group p*	Placebo Mean ± SD (n) Within-group p*	p RCT Fem™ UI vs. placebo* PollenBerry® vs. placebo*
Change from baseline at week 6	−0.06 ± 1.11 (32) 0.75	0.15 ± 0.87 (33) 0.32	0.18 ± 1.45 (38) 0.44	0.42 0.91
Change from baseline at week 12	−0.32 ± 0.98 (29) 0.08	0.16 ± 0.93 (31) 0.34	−0.24 ± 0.88 (38) 0.11	0.71 0.08
Change from baseline at week 18	−0.17 ± 2.22 (29) 0.68	−0.25 ± 0.75 (28) 0.09	−0.21 ± 0.81 (38) 0.12	0.93 0.84
Change from baseline at week 24	−0.52 ± 1.26 (25) 0.05†	−0.12 ± 0.74 (24) 0.42	−0.38 ± 0.89 (37) 0.01†	0.63 0.23

*The p values for between-group and within-group differences were generated using linear mixed-effects models.

^†Indicates a significant within-group difference from baseline.

SD = standard deviation; UI = urinary incontinence.