Figure 1. Effects of Rh123 on cell growth.

MCF-7, MCF-7/AdrVp1000 and MCF-7/Mitox cells were seeded at 1000–2000 cells/well in 24-well plates and grown in the absence or presence of increasing concentrations of Rh123 (0–400 μM). Cell viability was estimated 6 days later by staining the surviving cell colonies with 0.1% Methylene Blue in 50% (v/v) ethanol. Cell growth is expressed as a percentage of the control in the absence of drug. Each point is the mean±S.D. of three independent experiments.