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. Author manuscript; available in PMC: 2025 Jun 1.
Published in final edited form as: Stroke. 2024 May 16;55(6):1525–1534. doi: 10.1161/STROKEAHA.124.046694

Table 3 –

Clinical and Imaging Outcomes Upon Arrival In the Comprehensive Center According To The Inter-Hospital Arterial Recanalization Status

Overall
N=520
Recanalization
N=111
No Recanalization
N=409
P-value
NIHSS change during transfer (n=502)a 0 (−3 ; 2) −6 (−9 ; −1) 0 (−2 ; 2) <0.01
Infarct growth, mL (n=313)b 8.7 (1.4–23.9) 1.5 (0–11.7) 11.6 (2.1–25.9) <0.01
 MRI-to-MRI (n=136) 3.8 (0.8–18.8) 0 (0–2.9) 7.2 (1.4–19.7) <0.01
 CTP-to-MRI (n=177) 12.2 (2.5–26.6) 3.2 (0.5–20.0 13.8 (4.8–28.6) <0.01
Any hemorrhagic transformation (n=479)c 23 (5) 8 (8) 15 (4) 0.14
Endovascular therapy performed 324 (62) 23 (21) 301 (74) <0.01

Categorical variables are expressed as numbers (%) and continuous variables as median (interquartile range).

a:

Defined as NIHSS at the comprehensive center – NIHSS at the referring hospital. A negative value indicates clinical improvement and a positive value clinical deterioration. Data missing in 18/520 (3%) patients (2 [2%] in the recanalization group and 16 [4%] in the non recanalization group).

b:

Infarct growth was assessed in patients with MRI in both hospitals, or with CT-perfusion in the referring hospital and MRI upon arrival in the comprehensive center (see Methods for details). Data was missing in 207/520 (40%) patients (46 [41%] in the recanalization group and 161 [39%] in the non recanalization group).

c:

Inter-hospital hemorrhagic transformation was not available in 41/520 (8%) patients with direct transfer to angiosuite (i.e. lack of non-invasive control imaging upon arrival in the comprehensive center); 4 [4%] in the recanalization group and 37 [9%] in the non recanalization group).