Table 3:
Relative risk associated with progression to device implant/Stage 2 procedure within 90 days of PNE or Stage 1, following exclusion of deaths within 1 year.
| Basic Statistics | Univariate Model RR | Multivariate Model RR | |||||
|---|---|---|---|---|---|---|---|
| Variable Name | Total, N (%) N=907 (100.0) | Event, n (%) 530 (58.4) | P value | Relative risk (RR, 95% CI) | P value | RR, 95% CI | P value |
| Index procedure | |||||||
| PNE | 657 (72.4) | 349 (65.8) | <0.001 | Ref. | <0.001 | Ref. | <0.001 |
| Stage 1 | 250 (27.6) | 181 (34.2) | 1.36 (1.23 – 1.51) | 1.34 (1.21 – 1.49) | |||
| Age in years | |||||||
| 65–74 | 340 (37.5) | 202 (38.1) | 0.448 | Ref. | 0.456 | Ref. | 0.612 |
| 75–84 | 397 (43.8) | 236 (44.5) | 1.00 (0.89 – 1.13) | 1.01 (0.90 – 1.14) | |||
| ≥85 | 170 (18.7) | 92 (17.4) | 0.91 (0.77 – 1.07) | 0.94 (0.80 – 1.10) | |||
| Sex | |||||||
| Male | 231 (25.5) | 111 (20.9) | <.001 | Ref. | <0.001 | Ref. | 0.001 |
| Female | 676 (74.5) | 419 (79.1) | 1.29 (1.11 – 1.49) | 1.26 (1.09 – 1.46) | |||
| Race | |||||||
| White | 836 (92.2) | 492 (92.8) | 0.382 | Ref. | 0.389 | Ref. | 0.501 |
| Non-white | 71 (7.8) | 38 (7.2) | 0.91 (0.73 – 1.14) | 0.93 (0.74 – 1.16) | |||
| Charlson Comorbidity Index | |||||||
| 0 | 114 (12.6) | 64 (10.2) | 0.794 | Ref. | 0.795 | Ref. | 0.864 |
| 1–3 | 461 (50.8) | 268 (50.6) | 1.04 (0.87 – 1.24) | 1.03 (0.85 – 1.23) | |||
| ≥4 | 332 (36.6) | 198 (37.4) | 1.06 (0.88 – 1.28) | 1.05 (0.86 – 1.28) | |||
| Claims-based Frailty Index | |||||||
| Not Frail or Prefrail (CFI<0.25) | 161 (17.8) | 92 (17.4) | 0.391 | Ref. | 0.387 | Ref. | 0.518 |
| Mildly Frail (0.25 ≤ CFI < 0.35) | 466 (51.4) | 265 (50.0) | 1.00 (0.85 – 1.16) | 0.96 (0.82 – 1.12) | |||
| Moderate To Severely Frail (CFI ≥ 0.35) | 280 (30.9) | 173 (32.6) | 1.08 (0.92 – 1.27) | 1.02 (0.86 – 1.21) | |||
| Area Deprivation Index National Quartile | |||||||
| Q1 (ADI 1 – 32) | 187 (20.6) | 99 (18.7) | 0.280 | Ref. | 0.286 | Ref. | 0.396 |
| Q2 (ADI 32 – 50) | 212 (23.4) | 130 (24.5) | 1.16 (0.97 – 1.38) | 1.14 (0.96 – 1.35) | |||
| Q3 (ADI 50 – 67) | 234 (25.8) | 143 (27.0) | 1.15 (0.97 – 1.37) | 1.12 (0.95 – 1.33) | |||
| Q4 (ADI ≥ 68) | 273 (30.1) | 157 (29.6) | 1.09 (0.92 – 1.29) | 1.06 (0.90 – 1.26) | |||
Note: Residents who underwent simultaneous Stage 1 and 2 procedures were excluded from this analysis. Model adjusted for procedure year.
Abbreviations: ADI, Area Deprivation Index; CCI, Charlson Comorbidity Index; CFI, Claims-based Frailty Index; PNE, percutaneous nerve evaluation.