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. 2004 Jul 27;381(Pt 3):735–741. doi: 10.1042/BJ20040302

Table 3. Inhibition constants (Ki) for triclosan binding to wild-type and mutant PfENR.

Enzyme Inhibition constant (Ki) (nM)
Wild-type 0.03 (±0.001)
A217V 232.0 (±5.0)
A217G 0.57 (±0.05)
N218A 2.10 (±0.10)
N218D 1.50 (±0.04)
M281A 9.34 (±0.81)
M281T 10.0 (±0.89)
F368A 7.20 (±0.90)
F368I 6.30 (±0.56)