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. 2004 Jul 27;381(Pt 3):779–794. doi: 10.1042/BJ20031748

Table 3. Binding of coagulation factors to thrombin-activated platelets: theoretical resultsa.

Ligand Two other factors Number of binding sites/platelet (n) Kd (app) (nM)
fIXa Absentb 250 2.57
Presentc 250 0.69
fVIIIa Absentb 750 1.5
Presentc 926 (750 and 193)d 1.1 (1.5 and 0.34)d
fX Absentb 16000 320
Presentc 16002 and 755d 320 and 28.7d

a The conditions of calculations are given in the legend to Figure 5.

b Fixed values.

c Obtained values.

d Fitting to the two-site binding model.