Table 2.
Cognitive performance outcomes the next day after evening administration of THC/CBD and placebo
| Placebo; Actual/potential obs | THC/CBD; Actual/potential obs | p value | Cohen’s d [95% CI] | |
|---|---|---|---|---|
| DSST | ||||
| Number correct, n | 29.3 (10.5); 20/20 | 29.5 (7.1); 20/20 | 0.901 | -0.03 [-0.46, 0.41] |
| % Response accuracy | 91.8 (8.9); 20/20 | 90.7 (8.7); 20/20 | 0.723 | -0.08 [-0.52, 0.36] |
| DAT | ||||
| Tracking errors, pixels | 30.0 (11.0); 20/20 | 34.2 (25.1); 20/20 | 0.447 | 0.17 [-0.27, 0.61] |
| Response time, ms | 1288.5 (316.5); 20/20 | 1213.6 (268.1); 20/20 | 0.317 | -0.23 [-0.68, 0.23] |
| Number correct, n | 21.6 (2.3); 20/20 | 21.9 (2.1); 20/20 | 0.597 | 0.13 [-0.32, 0.58] |
| PSAT | ||||
| Number correct, n | 43.6 (12.2); 20/20 | 42.0 (16.1); 20/20 | 0.550 | -0.14 [-0.58, 0.31] |
| Response time, ms | 1632.1 (126.6); 20/20 | 1653.0 (156.2); 20/20 | 0.477 | 0.16 [-0.28, 0.60] |
| WPT | ||||
| % Retention | 90.4 (9.9); 20/20 | 92.3 (9.9); 20/20 | 0.377 | 0.16 [-0.28, 0.60] |
| FTT | ||||
| Pre-training learning | 18.2 (1.1); 18/20 | 18.1 (1.1); 20/20 | 0.839 | -0.11 [-0.55, 0.33] |
| Post-training learning | 21.9 (4.0); 18/20 | 22.2 (4.0); 20/20 | 0.267 | 0.13 [-0.31, 0.57] |
| Early retest learning | 20.0 (7.2); 18/20 | 20.4 (5.9); 20/20 | 0.739 | 0.07 [-0.37, 0.51] |
| Late retest learning | 31.7 (18.4); 18/20 | 33.4 (17.4); 20/20 | 0.476 | 0.15 [-0.29, 0.59] |
| Overnight early improvement | 100.9 (15.8); 18/20 | 91.4 (19.3); 20/20 | 0.210 | -0.25 [-0.69, 0.19] |
| Overnight late improvement | 152.2 (66.7); 18/20 | 150.0 (70.1); 20/20 | 0.695 | -0.05 [-0.49, 0.39] |
| Stroop Test | ||||
| % Colour accuracy | 99.2 (1.8); 20/20 | 97.8 (2.3); 20/20 | 0.016 | -0.60 [-1.08, -0.13] |
| Colour RT, s | 1.3 (0.3); 20/20 | 1.4 (0.3); 20/20 | 0.288 | 0.25 [-0.20, 0.70] |
| % Word accuracy | 99.8 (0.8); 20/20 | 93.6 (20); 20/20 | 0.182 | -0.31 [-0.76, 0.14] |
| Word RT, s | 1.4 (0.2); 20/20 | 1.4 (0.3); 20/20 | 0.967 | 0.01 [-0.43, 0.45] |
| N-back | ||||
| % 1-Back accuracy | 87.6 (9.7); 19/20 | 86.5 (10.9); 20/20 | 0.472 | -0.14 [-0.58, 0.31] |
| % 2-Back accuracy | 89.4 (7.8); 19/20 | 89.5 (7.8); 20/20 | 0.849 | 0.02 [-0.42, 0.46] |
Actual/potential obs depicts missing data by giving the amount of observed and recorded data being used by the mixed model compared with the potential number of observations (i.e., complete data). Values are mean (SD) unless otherwise stated. Abbreviations: DAT Divided Attention Task, DSST Digit Symbol Substitution Task, FTT Finger Tapping Task, PSAT Paced Serial Addition Task, RT reaction time, WPT Word Pairs Task. Bold font indicates significant difference p<0.05