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. 2024 Jan 8;202(10):4654–4673. doi: 10.1007/s12011-023-04043-x

Table 3.

Impact of different interventions on the anxiety-like behaviors of the adult male rats in the open field test

Measurements Rearing (freq) Licking (freq) Scratching (freq) Freezing time (sec) Fecal pellets (n) Urination (freq)
Control 24.00±1.00c 6.50±0.76c 2.67±0.33c 4.50±0.76c 9.00±0.58c 8.83±0.79c
ZnONP-5 18.67±0.49d 1.50±0.22d 0.83±0.31d 2.33±0.33d 2.83±0.60d 1.50±0.22d
ZnONP-10 27.00±1.59b 11.67±0.67b 5.17±0.48b 10.17±0.60b 12.00±0.73b 12.50±0.76b
BZnO-5 22.17±0.95c 8.00±0.58c 2.17±0.31c 6.33±0.88c 7.67±0.49c 8.33±0.49c
BZnO-10 36.67±0.71a 14.50±0.76a 7.17±0.60a 15.50±0.76a 15.83±1.01a 15.83±0.95a

The data were expressed as mean ± SEM, and statistical analysis was performed using one-way analysis of variance (ANOVA) followed by Duncan’s multiple range test for multiple comparisons. In the column, mean values labeled with different letters (a, b, c, d) were significantly different at a significance level of P < 0.0001