Table 3. Effect of lysine at the end of the CGHC motif on the isomerase activity.
hP5, hPDI and their mutants | Isomerase activity (%) |
---|---|
hP5 | 100.00 |
hP5-Q40K | 145.24 |
hP5-m2 | 75.00 |
hP5-m2Q40K | 135.37 |
hP5-m2Q40R | 67.72 |
hP5-m1K175Q | 41.77 |
hP5-m1 | 50.00 |
hP5-m12 | 0.00 |
hPDI | 100.00 |
hPDI-m2 | 92.83 |
hPDI-m2K40Q | 68.50 |
hPDI-m2K40R | 80.23 |
hPDI-m12 | 0.00 |