Table 3. Areas of interacting helical surfaces for the self-association of S100P and its interaction with S100A1.
Area (Å2)* | ||
---|---|---|
Helical interfaces | S100P/S100A1 | S100P/S100P |
Helix1/helix1 | 797 | 835 |
Helix4/helix4 | 791 | 707 |
Helix1/helix4 | 1016 | 905 |
Other contacts | 519 | 455 |
Total contact area | 3123† | 2902† |
* Areas were calculated using the computer program GRASP.
† The total contact area of the heterodimer is slightly larger (nearly 8%) than that of the homodimer, suggesting that the heterodimer may be more stable than the homodimer.