Table 1. Patient Characteristics by Cohort.
| Characteristic | Pre–vaccine availability | Vaccinated | Unvaccinated | |||
|---|---|---|---|---|---|---|
| No. (%) | COVID-19 diagnoses | No. (%) | COVID-19 diagnoses | No. (%) | COVID-19 diagnoses | |
| Total, No. | 18 648 606 | 1 012 335 | 14 035 286 | 866 469 | 3 242 215 | 149 745 |
| Sex | ||||||
| Female | 9 363 710 (50.2) | 543 513 | 7 308 556 (52.1) | 481 581 | 1 363 401 (42.1) | 79 179 |
| Male | 9 284 896 (49.8) | 468 825 | 6 726 730 (47.9) | 384 891 | 1 878 814 (57.9) | 70 569 |
| Age range, y | ||||||
| 18-29 | 3 278 187 (17.6) | 244 839 | 1 760 740 (12.5) | 94 533 | 981 925 (30.3) | 40 131 |
| 30-39 | 3 225 998 (17.3) | 203 931 | 1 958 328 (14) | 149 193 | 966 470 (29.8) | 50 655 |
| 40-49 | 3 059 107 (16.4) | 190 065 | 2 206 560 (15.7) | 236 229 | 612 180 (18.9) | 33 429 |
| 50-59 | 3 264 621 (17.5) | 184 371 | 2 716 818 (19.4) | 204 009 | 376 272 (11.6) | 16 827 |
| 60-69 | 2 552 894 (13.7) | 92 931 | 2 316 757 (16.5) | 105 645 | 186 402 (5.7) | 5625 |
| 70-79 | 2 066 329 (11.1) | 51 573 | 1 980 447 (14.1) | 54 057 | 80 546 (2.5) | 1947 |
| 80-89 | 989 819 (5.3) | 31 893 | 909 927 (6.5) | 18 327 | 30 138 (0.9) | 903 |
| ≥90 | 211 651 (1.1) | 12 717 | 185 709 (1.3) | 4479 | 8282 (0.3) | 225 |
| Ethnicitya | ||||||
| Black | 1 191 793 (6.4) | 118 365 | 789 476 (5.6) | 41 457 | 325 199 (10) | 9609 |
| South Asian | 217 132 (1.2) | 14 241 | 128 514 (0.9) | 7521 | 81 017 (2.5) | 3867 |
| White | 14 865 866 (79.7) | 773 745 | 11 752 297 (83.7) | 748 743 | 2 025 492 (62.5) | 115 449 |
| Mixed | 423 111 (2.3) | 20 301 | 237 383 (1.7) | 10 641 | 190 874 (5.9) | 4035 |
| Otherb | 400 437 (2.1) | 27 069 | 217 317 (1.5) | 9585 | 173 014 (5.3) | 7641 |
| Missing | 1 550 267 (8.3) | 58 611 | 910 299 (6.5) | 48 513 | 446 619 (13.8) | 9141 |
| IMD quintile | ||||||
| 1 | 3 574 653 (19.2) | 247 365 | 2 273 863 (16.2) | 135 945 | 958 877 (29.6) | 45 795 |
| 2 | 3 690 808 (19.8) | 219 063 | 2 617 493 (18.6) | 158 889 | 775 318 (23.9) | 35 445 |
| 3 | 4 042 896 (21.7) | 203 055 | 3 111 723 (22.2) | 186 855 | 652 380 (20.1) | 29 619 |
| 4 | 3 809 548 (20.4) | 183 015 | 3 065 889 (21.8) | 191 499 | 498 458 (15.4) | 22 515 |
| 5 | 3 530 701 (18.9) | 159 837 | 2 966 318 (21.1) | 193 275 | 357 182 (11) | 16 371 |
| Smoking | ||||||
| Never | 759 965 (4.1) | 40 677 | 428 549 (3.1) | 16 419 | 370 770 (11.4) | 8415 |
| Formerly | 8 568 556 (45.9) | 504 843 | 6 540 674 (46.6) | 422 337 | 1 348 307 (41.6) | 59 631 |
| Currently | 6 137 311 (32.9) | 329 373 | 5 106 300 (36.4) | 333 675 | 645 817 (19.9) | 43 887 |
| Missing | 3 182 774 (17.1) | 137 439 | 1 959 763 (14) | 94 035 | 877 321 (27.1) | 37 815 |
| Region | ||||||
| East | 4 305 743 (23.1) | 227 421 | 3 281 525 (23.4) | 182 847 | 731 831 (22.6) | 33 825 |
| East Midlands | 3 263 511 (17.5) | 191 925 | 2 474 916 (17.6) | 161 259 | 527 562 (16.3) | 28 815 |
| London | 1 245 392 (6.7) | 67 791 | 728 567 (5.2) | 37 287 | 459 504 (14.2) | 10 977 |
| North East | 889 507 (4.8) | 60 369 | 663 394 (4.7) | 48 891 | 137 238 (4.2) | 7239 |
| North West | 1 658 370 (8.9) | 109 887 | 1 270 319 (9.1) | 88 227 | 220 722 (6.8) | 12 045 |
| South East | 1 249 245 (6.7) | 50 373 | 969 482 (6.9) | 57 105 | 195 663 (6) | 8853 |
| South West | 2 655 179 (14.2) | 80 649 | 2 207 972 (15.7) | 133 143 | 331 576 (10.2) | 17 871 |
| West Midlands | 760 648 (4.1) | 56 397 | 499 564 (3.6) | 29 931 | 181 504 (5.6) | 8223 |
| Yorkshire | 2 621 011 (14.1) | 167 505 | 1 939 547 (13.8) | 127 767 | 456 615 (14.1) | 21 891 |
| Care home resident | 90 076 (0.5) | 15 309 | 57 532 (0.4) | 2835 | 3014 (0.1) | 105 |
Abbreviation: IMD, Index of Multiple Deprivation (lower indicates more deprived).
a
Ethnicity data were reported because disparities in COVID-19 outcomes by ethnic group have been reported.17
b
Other ethnicity groups were consolidated for disclosure control.