Table. Baseline Characteristics of the Study Population.
Characteristic | All (N = 560), No. (%) |
---|---|
Age, median (IQR), y | 68 (59 to 74) |
Sex | |
Male | 346 (61.8) |
Female | 214 (38.2) |
SBP, median (IQR), mm Hg | 115 (105 to 130) |
Ischemic heart disease | 57 (10.2) |
Diabetes | 56 (10) |
Hypertension | 156 (27.9) |
Atrial fibrillation | 70 (12.5) |
eGFR, mL/min | 71 (55 to 90) |
NYHA class | |
I | 95 (19.4) |
II | 301 (61.4) |
III | 79 (16.1) |
IV | 15 (3.1) |
NT-proBNP, median (IQR), ng/L | 2148 (518 to 5751) |
Troponin T, median (IQR), ng/mL | 50 (24 to 106) |
κ/λ Ratio, median (IQR) | 8 (1.3 to 23.3) |
VGPR or CR at 1 mo | 167 (29.8) |
IVS, median (IQR), mm | 14 (11 to 16) |
RWT, median (IQR) | 0.62 (0.51 to 0.77) |
E/e′ ratio, median (IQR) | 12.7 (9.2 to 18.2) |
LVEF, median (IQR), % | 58 (51 to 62) |
GLS, median (IQR), % | −14.5 (−19.1 to −10.5) |
ECV, median (IQR), % | 0.45 (0.36 to 0.53) |
β-Blockers | 134 (23.9) |
ACEi/ARBs | 169 (30.2) |
Loop diuretic | 286 (51.1) |
MRAs | 64 (11.4) |
Abbreviations: ACEi, angiotensin-converting enzyme inhibitors; ARBs, angiotensin receptor blockers; CR, complete response; ECV, extracellular volume; E/e′, ratio of E-wave velocity to peak e′ velocity; eGFR, estimated glomerular filtration rate; GLS, global longitudinal strain; IVS, interventricular septum thickness; LVEF, left ventricular ejection fraction; MRAs, mineralocorticoid receptor antagonists; NT-proBNP, N-terminal pro–B-type natriuretic peptide; NYHA, New York Heart Association; RWT, relative wall thickness; SBP, systolic blood pressure; VGPR, very good partial response.