Table 2. Imaging features differentiating cardiac myxomas from thrombi and other cardiac masses.
Inversion time on LGE (late gadolinium enhancement) is a specific parameter used in cardiac MRI to nullify the signal from healthy myocardium, thus enhancing the visibility of abnormal tissues. MI = myocardial infarction.
Feature | Myxoma | Thrombus | Other tumors (e.g., fibroelastoma) |
Location | Left atrium, typically at fossa ovalis | Left atrium (appendage), left ventricle (post-MI) | Valvular endocardium or ventricular outflow tract |
Attachment | Narrow, often pedunculated | Broad-based | Narrow, with a pedicle |
Mobility | Highly mobile, may prolapse through AV valve | Less mobile | Highly mobile |
Shape | Lobulated, irregular | Smooth, more uniform | Small, often round or oval |
Size | Variable, can be large (up to 15 cm) | Typically smaller, variable | Generally small (<1 cm) |
Echotexture | Heterogeneous | Homogeneous | Homogeneous |
Borders | Well-defined | Less well-defined | Well-defined |
Functional Impact | Can obstruct AV valve during diastole | May impair ventricular function | Rarely obstructive, more likely embolic |
T1 Signal | Heterogeneous intermediate | Homogeneous hypointense | Homogeneous low |
T2 Signal | Heterogeneous hyperintense | Homogeneous hypointense | Homogeneous high |
Gadolinium Enhancement | Heterogeneous, variable | Typically no enhancement, unless organized | Uniform enhancement |
Inversion Time on LGE | 200–300 ms | 550–650 ms | N/A |
Perfusion | Delayed perfusion, heterogeneous uptake | No perfusion | Homogeneous uptake |
Calcification | Possible, seen in some cases | Rare, unless chronic | Rare |
Hemorrhage | Possible, seen in some cases | Rare | Rare |
Consistency | Soft, gelatinous | Firm, organized if chronic | Firm |