Table 2.
Respiratory Pathogen Panel Results for Paired Residual Nasal Antigen Swabs and Nasopharyngeal PCR Swabs (03/20–08/31/2023)a,b
| Swab Type | ||
|---|---|---|
| NP PCR (n = 58) | Nasal Ag (n = 58) | |
| Rhinovirus/enterovirus | 24 | 22 |
| Seasonal coronavirus | 20 | 18 |
| Human metapneumovirus | 9 | 8 |
| Parainfluenza | 5 | 3 |
| Influenza | 3 | 3 |
| SARS-CoV-2 | 2 | 2 |
| Adenovirus | 0 | 1b |
| RSV | 0 | 0 |
| Bocavirus | 0 | 0 |
| No virus detected | 0 | 5 |
| Total number of viruses detected | 63 | 57 |
Abbreviations: Ag, antigen; Ct, cycle threshold, NP, nasopharyngeal; PCR, polymerase chain reaction; Rp, human RNase P; RPP, Respiratory Pathogen Panel; RSV, respiratory syncytial virus.
aFifty-eight individuals with NP swabs that were positive on RPP for ≥1 virus were chosen for an RPP pilot study on Ag swabs. Among the 58 Ag swabs, we detected ≥1 virus on 53 swabs (91.4%). On Ag swabs, 56/63 viruses detected on NP swabs were also detected (88.9%). Overall agreement by Cohen's Kappa was 0.85.
bFor 1 person, the NP swab tested positive for rhinovirus/enterovirus only, but their paired Ag swab tested positive for both rhinovirus/enterovirus and adenovirus (NP Rp Ct, 26.5; nasal Ag Rp Ct, 28.8; nasal Ag adenovirus Ct, 40.8).