Anand 2013.

Study characteristics
Methods	Study design Parallel RCT Time frame: not reported Duration of follow‐up: 12 months Country: India Setting: single centre
Participants	Study characteristics Inclusion criteria: children with initial episode of SSNS Exclusion criteria: not reported Baseline characteristics Number (analysed/randomised): 60 randomised (numbers per group not reported) Age range: 1 to 12 years Sex (M/F): not reported
Interventions	Intervention group 1 Prednisolone: 4 weeks daily; then alternate‐day and tapered over 5 months. Daily dose not provided Total dose: 126.5 mg/kg over 6 months Total duration: 6 months Intervention group 2 Prednisolone: 6 weeks daily then 6 weeks alternate days. Daily doses not provided Total dose: 123.8 mg/kg over 3 months Total duration: 3 months
Outcomes	Outcomes relevant to this review Relapse rate by 12 months: 20% (treatment group 1) vs 76.7% (treatment group 2) Adverse effects
Notes	Additional information Abstract‐only publication: numbers of patients in each group not provided so data could not be included in the meta‐analysis Funding source: not reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Study described as randomised; method of randomisation not reported
Allocation concealment (selection bias)	Unclear risk	Insufficient information to permit judgement
Blinding of participants and personnel (performance bias) All outcomes	High risk	Not blinded
Blinding of outcome assessment (detection bias) All outcomes	High risk	Relapse defined by urinalysis done by family/staff
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Insufficient information to permit judgement
Selective reporting (reporting bias)	Unclear risk	Insufficient information to permit judgement
Other bias	Unclear risk	Insufficient information to permit judgement