Table 7. Micromolar (μM) GI50 Values for Doxorubicin Alone and in Combination with a MAO-A Inhibitor Clorgyline Treatment in Colorectal Cancer Cell Linesa.
| HCT116 |
Caco2 |
SW480 |
SW620 |
HT29 |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| time (h) | Doxo | Comb | Doxo | Comb | Doxo | Comb | Doxo | Comb | Doxo | Comb |
| 24 | 4.92 | 1.29 | 352.26 | 3.19 | NA | NA | 17.37 | 2.04 | 2.80 | 1.50 |
| 48 | 0.15 | 0.15 | 42.77 | 2.29 | NA | NA | 0.28 | 0.27 | 0.43 | 0.41 |
| 72 | 0.14 | 0.12 | 1.79 | 0.65 | NA | NA | 0.11 | 0.07 | 0.28 | 0.27 |
SD is not reported here since none exceeded 5%. h: hour; Doxo: doxorubicin; Comb: combination of doxorubicin and clorgyline [1:100] GI50 (μM).