Reprinted with
permission from ref (136). Copyright 2022 Elsevier. (A) The study includes
representative images of dendritic segments from cortical layer II/III
pyramidal neurons, visualized using Golgi staining on brain sections.
(B, C) Quantitative analysis was conducted to determine the density
of apical and basal dendritic segments in cortical layer II/III pyramidal
neurons, as well as spine density in hippocampus CA1 pyramidal neurons.
(D) Western blotting analysis was performed to detect specific protein
expression levels. (E, F) The study involved quantifying the levels
of Synapsin1 and PSD95 proteins in the cortex, providing insights
into synaptic protein dynamics. (G) Representative images obtained
through Transmission Electron Microscopy (TEM) illustrate the ultrastructure
of dorsal hippocampus neurons. The experimental conditions or treatments
mentioned (M, RBC-MIC hybrid membrane; CA, curcumin-aspirin esterl;
MI, minocycline; MCAGP, CA loading the graphene oxide quantum dots
nanosize carrier with the modification of a hybrid cell membrane)
were applied to investigate their effects on the observed parameters,
such as dendritic morphology and protein levels.