Table 2.
Baseline characteristics of the study population according to the TG/HDL-C ratio quartile groups
| TG/HDL-C ratio quartile | P-value | ||||
|---|---|---|---|---|---|
| Q1 (< 1.586) | Q2 (1.586–2.504) | Q3 (2.504–3.938) | Q4 (≥ 3.938 ) | ||
| No. of subjects | 3778 | 3780 | 3772 | 3777 | |
| Sociodemographic parameters | |||||
| Age; years, medians (Q1-Q4) | 48.00 (37.00–59.00) | 51.00 (39.00–61.00) | 52.00 (42.00–61.00) | 52.00 (42.00–61.00) | < 0.001 |
| Sex, n(%) | < 0.001 | ||||
| Male | 1790 (47.38) | 2366 (62.59) | 2668 (70.73) | 42,921 (77.34) | |
| Female | 1988 (52.62) | 1414 (37.41) | 1104 (29.27) | 856 (22.66) | |
| Anthropometric parameters | |||||
| BMI; kg/m2, mean (SD) | 22.96 ± 3.04 | 24.59 ± 3.13 | 25.46 ± 3.12 | 26.17 ± 3.07 | < 0.001 |
| Biochemical parameters | |||||
| SBP; mmHg, mean (SD) | 123.11 ± 17.57 | 127.38 ± 17.65 | 129.11 ± 17.37 | 130.12 ± 17.36 | < 0.001 |
| DBP; mmHg, mean (SD) | 75.23 ± 10.76 | 77.94 ± 11.11 | 79.64 ± 11.12 | 80.92 ± 10.90 | < 0.001 |
| FPG; mmol/L, mean (SD) | 5.89 ± 0.29 | 5.92 ± 0.30 | 5.97 ± 0.32 | 6.00 ± 0.33 | < 0.001 |
| TC; mmol/L, mean (SD) | 4.78 ± 0.88 | 4.98 ± 0.91 | 5.10 ± 0.93 | 5.24 ± 0.94 | < 0.001 |
| TG; mmol/L, mean (SD) | 0.75 ± 0.21 | 1.22 ± 0.23 | 1.74 ± 0.35 | 2.98 ± 1.05 | < 0.001 |
| HDL-C; mmol/L, medians (Q1-Q4) | 1.53 (1.36–1.71) | 1.38 (1.23–1.54) | 1.27 (1.12–1.43) | 1.10 (0.97–1.28) | < 0.001 |
| LDL-C; mmol/L, medians (Q1-Q4) | 2.72 (2.31–3.16) | 2.91 (2.48–3.37) | 2.98 (2.54–3.45) | 2.93 (2.48–3.45) | < 0.001 |
| ALT; U/L, medians (Q1-Q4) | 16.30 (12.20–23.00) | 20.80 (15.00-29.25) | 24.00 (17.10–35.00) | 28.50 (20.00-41.60) | < 0.001 |
| AST; U/L, medians (Q1-Q4) | 21.90 (18.00–26.00) | 23.40 (19.70–28.30) | 24.00 (20.50–29.00) | 26.00 (21.50–32.00) | < 0.001 |
| BUN; mmol/L, medians (Q1-Q4) | 4.86 (4.09–5.72) | 4.90 (4.14–5.80) | 4.90 (4.14–5.77) | 4.84 (4.10–5.70) | 0.043 |
| Cr; umol/L, medians (Q1-Q4) | 67.00 (57.00-79.40) | 72.80 (61.00–83.00) | 75.00 (63.65-85.00) | 75.60 (65.10–85.10) | < 0.001 |
| Family history of diabetes, n(%) | 101 (2.67) | 88 (2.33) | 103 (2.73) | 103 (2.73) | 0.646 |
| Lifestyle parameters | |||||
| Smoking status, n(%) | < 0.001 | ||||
| Current | 683 (18.08) | 843 (22.3) | 950 (25.19) | 1202 (31.83) | |
| Ever | 160 (4.24) | 167 (4.43) | 203 (5.38) | 259 (6.85) | |
| Never | 2935 (77.68) | 2770 (73.27) | 2619 (69.43) | 2316 (61.32) | |
| Drinking status, n(%) | < 0.001 | ||||
| Current | 146 (3.87) | 163 (4.32) | 205 (5.43) | 233 (6.17) | |
| Ever | 578 (15.31) | 620 (16.4) | 700 (18.55) | 832 (22.04) | |
| Never | 3053 (80.82) | 2997 (79.28) | 2867 (76.02) | 2712 (71.79) | |
Values were expressed as mean (standard deviation) or medians (quartile1- quartile 4) or n (%)
Abbreviations: BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose; TG: triglyceride; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; ALT: alanine aminotransferase; AST: aspartate aminotransferase; BUN: blood urea nitrogen; Cr: creatinine