Table 2. Effect of vasodilator drugs and CCCP on transport of adenosine by AtENT4, 6 and 7.
Adenosine was provided at a concentration of 25 μM (AtENT4), 1.8 μM (AtENT6) and 5 μM (AtENT7) and yeast cells were incubated for 2 min together with the indicated effectors. Results are means±S.E.M. for three independent experiments.
| Transporter (residual activity, %) | |||
|---|---|---|---|
| Inhibitor | AtENT4 | AtENT6 | AtENT7 |
| Dilazep (20 nM) | 71.5±17.0 | 76.3±3.8 | 81.7±4.3 |
| Dilazep (20 μM) | 30.0±12.0 | 17.9±1.1 | 27.5±5.6 |
| NBMPR (20 nM) | 79.3±7.0 | 86.7±6.6 | 84.0±4.8 |
| NBMPR (20 μM) | 17.7±9.0 | 14.5±1.0 | 62.3±3.9 |
| CCCP (50 μM) | 52.0±17.0 | 31.5±2.5 | 76.0±2.5 |