Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Aug 21;13(1):2393442. doi: 10.1080/2162402X.2024.2393442

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2024 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

PMC Copyright notice

Figure 6. — M1 macrophage -secreted factors simulate stemness gene expression pattern through NFκB signaling. (a) Enrichment of hallmark gene sets in pairwise comparisons in LNCaP cells treated with M0 or M1 CM, or M1 CM with IKK16 inhibitor (NFκBi) or DMSO. NES: normalized enrichment score, adjusted p-value <0.05. (b) GSEA from gene sets related to stem cell characteristics. (c) The effects of M1 CM NFκBi or DMSO on the expression of NANOG, KLF4, OCT4, SOX2 and CD44. The data represents mean ± SD. Statistical significances were tested with the Mann–Whitney test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.