Figure 3. PPARα–AMPKα interaction in vivo.
293 cells were transfected with expression plasmids for mPPARα (0.2 μg) and FLAG–hAMPKα2 (1.0 μg) as indicated. (A) mPPARα complexes were immunoprecipitated with anti-mPPARα antiserum, immunoprecipitates were resolved by SDS/PAGE and FLAG–hAMPKα2 complexes were characterized by Western blotting using anti-FLAG M2 monoclonal antiserum as described in the Experimental section. (B) Expression of FLAG–hAMPKα2 was monitored by Western blotting of cell lysates using anti-FLAG antisera. Kd, kDa.