Table 1.
Differences between BDNF Met-carriers and Val homozygotes at baseline.
| Met-carriers N = 37 |
Val homozygotes N = 17 |
||||||
|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Statistic | df | P | |
| Age | 34.19 | 7.52 | 32.06 | 7.54 | t = 0.967 | 52 | 0.338 |
| Education | 14.50 | 4.04 | 14.88 | 2.89 | t = −0.35 | 52 | 0.728 |
| Female/male | 22/15 | 9/8 | χ² = 0.202 | 1 | 0.653 | ||
| Han nationality/non | 33/4 | 16/1 | NA | NA | 1.000 | ||
| Employment/non | 15/22 | 8/9 | χ² = 0.202 | 1 | 0.653 | ||
| Marriage/non | 16/21 | 5/12 | χ² = 0.938 | 1 | 0.333 | ||
| Current smoker/non | 3/34 | 3/14 | NA | NA | 0.365 | ||
| Clozapine user/non | 8/29 | 1/16 | χ² = 1.099 | 1 | 0.295 | ||
| Chlorpromazine equivalents | 441.18 | 314.11 | 443.88 | 213.70 | t = −0.032 | 52 | 0.974 |
| Duration of illness | 12.14 | 8.51 | 9.48 | 7.09 | t = 1.124 | 52 | 0.266 |
| PANSS positive | 9.73 | 3.84 | 7.65 | 1.54 | t = 2.839 | 51 | 0.006 |
| PANSS negative | 12.86 | 4.60 | 11.47 | 3.56 | t = 1.105 | 52 | 0.274 |
| PANSS general | 22.11 | 4.86 | 18.76 | 2.51 | t = 3.325 | 51 | 0.002 |
| PANSS total | 44.70 | 9.14 | 37.88 | 6.19 | t = 2.789 | 52 | 0.007 |
| K_T2 (N: 34/17) | 1.36 | 0.47 | 1.52 | 0.34 | t = −1.235 | 49 | 0.223 |
| K_T4 (N: 34/17) | 1.59 | 0.80 | 2.11 | 0.59 | t = −2.356 | 49 | 0.023 |
| Filtering efficiency_T2 (N: 34/17) | 0.27 | 0.28 | 0.26 | 0.29 | t = 0.174 | 49 | 0.863 |
| Filtering efficiency_T4 (N: 34/17) | 0.70 | 0.43 | 0.84 | 0.44 | t = −1.014 | 49 | 0.315 |
| MMN amplitude (N: 36/17) | −2.83 | 1.64 | −3.02 | 1.65 | t = 0.377 | 51 | 0.708 |
BDNF, brain-derived neurotrophic factor, PANSS positive and negative syndrome scale, K_T2 Cowan’s K under only two targets condition of the change detection task, K_T4 Cowan’s K under only four targets condition of the change detection task, Filtering efficiency_T2 filtering efficiency for two targets, Filtering efficiency_T4 filtering efficiency for four targets, MMN mismatch negativity.