Table 4.
Performance of ‘severity score’ and ‘Impaired IL-10 response’ as diagnostic test identifying outcome of COVID-19.
| Statistics | Performance of ‘Severity Score’ | Performance of ‘impaired IL-10 response’ | |||||||
|---|---|---|---|---|---|---|---|---|---|
| COVID-19 outcome: Requiring ICU support /death (No comorbidity) | COVID-19 outcome: Requiring ICU support /death (with or without comorbidity) | COVID-19 outcome: Requiring O2/ICU support /Death, No comorbidity | COVID-19 outcome: Requiring O2/ICU support /death (with or without comorbidity) | ||||||
| Yes (N) | No (N) | Yes (N) | No (N) | Yes (N) | No (N) | Yes (N) | No (N) | ||
| Confusion Matrix | Risk Detected | 10 | 2 | 17 | 2 | 9 | 6 | 16 | 7 |
| Risk not detected | 1 | 25 | 5 | 31 | 5 | 28 | 15 | 29 | |
| Total | 11 | 27 | 22 | 33 | 14 | 34 | 31 | 36 | |
| Test performance | % (95% CI) | % (95% CI) | % (95% CI) | % (95% CI) | |||||
| Sensitivity | 91 (58.7 -99.8) | 77.3 (54.6–92.2) | 64.2 (35.1–87.2) | 51.6 (33.1–69.8) | |||||
| Specificity | 92.6 ( 75.7–99) | 93.9 (79.8–99.3) | 82 (65.5–93.2) | 80.5 (64.0–91.8) | |||||
Risk detected: Severity score > 12 or ‘Impaired IL-10 response’ detected; Risk not detected: Severity score < 12 or ‘Impaired IL-10 response’ not detected; N: Number of cases, CI: Confidence Interval.