TABLE 2.
Reference | Gender | Age (years) | Underlying disease | Manifestation | Peripheral blood WBC (×109/L) | CSF WBC (×106/L) | CSF protein (mg/dL) | Diagnostic method | Treatment | Outcome |
---|---|---|---|---|---|---|---|---|---|---|
Hansen et al. 4 | F | 1.5 | Hydrocephaly and CSF shunt | Fever, meningeal signs, enlargement of the cranical perimeter | n.a. | 1400 | 75 | CSF culture | Methicillin; chloramphenicol; penicillin | Recovered |
Berger and Kreissel 5 | M | 4 | Not found | Vomiting, somnolence, fever | 14.3 | 14,850 | 325 | CSF culture | Penicillin | Recovered |
Fritsche et al. 6 | F | 4 | Not found | Fever, headache, cold, cough, skin sports | 16.0 | n.a. | 16.4 | CSF culture | Penicillin | Recovered |
Fijen et al. 7 | M | 15 | Complement C8 deficiency | Fever, vomiting, petechiae, meningeal irritability, disturbance of consciousness | n.a. | 82 | n.a. | CSF culture | Penicillin | Recovered |
Roh et al. 8 | F | 4 | Not found | Headache, fever, abdominal pain, vomiting | 19.8 | 890 | 31 | CSF culture; 16S rRNA gene sequence | Cefotaxime; ampicillin | Recovered |
Roh et al. 8 | M | 15 | Not found | Headache, petechiae, neck stiffness | 30.2 | 35,500 | 575 | CSF culture; 16S rRNA gene sequence | Ceftazidime; netilmicin | Recovered |
Roh et al. 8 | M | 81 | Pancreatic cancer and liver cirrhosis | Headache, petechiae, neck stiffness | 6.9 | 9 | 75 | CSF culture; 16S rRNA gene sequence | Cefotaxime | Recovered |
Fox‐Lewis et al. 9 | F | 31 | Subclinical sinusitis | Rapid onset confusion, neck stiffness, headache | n.a. | 92 | 325 | CSF 16S rDNA PCR screening | Chloramphenicol; doxycycline | Recovered |
Abbreviations: F, female; M, male; n.a., not available.