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[Preprint]. 2024 Aug 13:2024.08.12.607658. [Version 1] doi: 10.1101/2024.08.12.607658

Figure 5: Calcium transients in stereocilia appear to be independent of whole cell spontaneous activity.

Figure 5:

A) An example of P0 ampullar hair cells containing stereocilia with calcium transients but no spontaneous activity in the cell body. An example of cells exhibiting cell body activity and calcium transients in stereocilia is shown in Supplemental Movie 7. Scale bar is 5 μm. B) DHS treatment (1 mM) does not affect the spontaneous activity in the hair cell body, which is controlled by purinergic signaling and does not require a functional MET channel. Cultured P2 organs of Corti are shown here with cytoplasmic expression of GCaMP6F. Scale bar is 5 μm.